The new frontiers of diagnostics, such as personalized medicine, patient domiciliation, precision agriculture and food control in every point of the supply chain, requires new analysis methods based on rapid, easy, transportable and economic methods, maintaining a reliability standard at laboratory level. PoC (Point of Care) summarizes this new concept of monitoring. The analysis is performed where they are needed, a bed, a house, a clinic, a factory or a field. POC biochemical analysis are challeging, but the potential impact is enormous. LOCs, Laboratory on Chips, are currently enjoying a lot of interest in the field of diagnostics. LOCs are glass or polymer devices in which biological protocols are performed in a few square centimeters. There are several applications, but substantially the three main categories are cell sorting, genomic analysis (DNA, RNA) and immuno-enzymatic analysis.
EliChipTM fits in this latter context. EliChipTM is an innovative system for performing POC enzyme immunoassays, based on a disposable LoC card and a reader for handling reagents and reading the results.
EliChipTM allows non-specialized personnel to perform quantitative low-cost analysis on single sample.
The validity of the method and its feasibility have been demonstrated with an alpha prototype. EliChipTM is ready for the industrialization.
Food control
Veterinary diagnostics
Medical diagnostics
Disposable and ready to use Lab-on-Chip (LOC) cards containing immunoassays reagents
Portable, ready to use, automated reader able to manage the microfluidics protocols, read and display results and connect to devices: USB or wifi
Insert the sample in the card
Plug the card into the reader
Result in 20-60 min.
Insert the sample in the card
Plug the card into the reader
Result in 20-60 min.
Rapid test | EliChip | Lab Analysis | |
Time to results | Minutes | Minutes/hours | Hours/days |
On-field analysis | yes | yes | no |
Skilled operator | Not requested | Not requested | Compulsory |
Sample preparation | Sometimes | Sometimes | Sometimes |
Test cost | low | low | Medium-high |
Instrumentation cost | low | low | high |
Quantitative | no | yes | yes |
Selectivity | low | High (as ELISA) | high |
Accuracy | low | High (as ELISA) | high |
Sensitivity | low | High (as ELISA) | high |
Allergens:
Gliadin
Lysozyme
Micotoxines:
AB1
AM1
OTA
Virus:
BVD
Leishmania
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